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Pathogenic Fungi

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A 4-year-old boy was taken by his mother to the family doctor for evaluation of a 2-month history of a slowly growing “bump” on the back of his head. The boy had no other siblings or any pets at home. He attended a day care center weekdays while his mother worked. Examination revealed a happy, alert child in no distress. A raised, scaling lesion 3.5 cm in diameter with a few pinpoint pustules was present on the posterior scalp. A KOH preparation of material from the lesion was negative. A fungal culture of material from the lesion was later positive for a fungus with numerous microconidia and macroconidia typical of Microsporum species.

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What is the most likely source of this child's infection?

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A. Parents

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B. Child at day care center

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C. Animal

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D. Insect

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E. Food

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A 4-year-old boy was taken by his mother to the family doctor for evaluation of a 2-month history of a slowly growing “bump” on the back of his head. The boy had no other siblings or any pets at home. He attended a day care center weekdays while his mother worked. Examination revealed a happy, alert child in no distress. A raised, scaling lesion 3.5 cm in diameter with a few pinpoint pustules was present on the posterior scalp. A KOH preparation of material from the lesion was negative. A fungal culture of material from the lesion was later positive for a fungus with numerous microconidia and macroconidia typical of Microsporum species.

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What is the human niche where this organism proliferates best?

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A. Fibronectin

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B. Macrophages

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C. M cells

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D. Keratin

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A 4-year-old boy was taken by his mother to the family doctor for evaluation of a 2-month history of a slowly growing “bump” on the back of his head. The boy had no other siblings or any pets at home. He attended a day care center weekdays while his mother worked. Examination revealed a happy, alert child in no distress. A raised, scaling lesion 3.5 cm in diameter with a few pinpoint pustules was present on the posterior scalp. A KOH preparation of material from the lesion was negative. A fungal culture of material from the lesion was later positive for a fungus with numerous microconidia and macroconidia typical of Microsporum species.

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What additional examination might have revealed this infection while the child was in the doctor's office?

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