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Chapter 10. Diagnostic Testing

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In raising the cutoff point for a screening test, which of the following is the likely result?

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A. An increase in sensitivity

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B. An increase in specificity

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C. An increase in false positives

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D. An increase in prevalence

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E. An increase in lead time bias

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If the screening test does not delay the time of death from a condition but makes survival appear longer because of earlier detection of disease, there is evidence of

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A. confounding.

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B. length-biased sampling.

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C. lead time bias.

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D. selection bias.

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E. information bias.

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A test with an LR+ of 15 can be said to provide evidence to

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A. rule in the condition of interest.

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B. rule out the condition of interest.

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C. make an earlier diagnosis.

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D. prolong survival after diagnosis.

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E. detect slowly progressing forms of the condition of interest.

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A specific diagnostic test is one that

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A. has a high proportion of false-negative results.

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B. has a low proportion of false-negative results.

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C. has a high proportion of false-positive results.

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D. has a low proportion of false-positive results.

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E. none of the above.

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A diagnostic test with no discriminatory ability would have an area under the ROC curve of

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A. 0.

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B. 0.25.

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C. 0.5.

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D. 1.

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E. 2.

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A diagnostic test with an LR- of 0.05 can be said to provide evidence to

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A. rule in the condition of interest.

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B. rule out the condition of interest.

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C. make an earlier diagnosis.

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D. prolong survival after diagnosis.

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