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Chapter 11. Toxic Responses of the Blood

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Which of the following statements is FALSE regarding true anemia?

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a. Alterations of the mean corpuscular volume are characteristic of anemia.

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b. Increased destruction of erythrocytes can lead to anemia.

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c. Decreased production of erythrocytes is not a common cause of anemia because the bone marrow is continuously renewing the red blood cell pool.

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d. Reticulocytes will live for a longer period of time in the peripheral blood when a person is anemic.

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e. The main parameters in diagnosing anemia are RBC count, hemoglobin concentration, and hematocrit.

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Which of the following types of anemia is properly paired with its cause?

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a. iron deficiency anemia—blood loss.

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b. sideroblastic anemia—vitamin B12 deficiency.

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c. megaloblastic anemia—folate supplementation.

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d. aplastic anemia—ethanol.

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e. megaloblastic anemia—lead poisoning.

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The inability to synthesize the porphyrin ring of hemoglobin will most likely result in which of the following?

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a. iron deficiency anemia.

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b. improper RBC mitosis.

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c. inability to synthesize thymidine.

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d. accumulation of iron within erythroblasts.

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e. bone marrow hypoplasia.

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Which of the following will cause a right shift in the oxygen dissociation curve?

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a. increased pH.

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b. decreased carbon dioxide concentration.

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c. decreased body temperature.

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d. increased 2,3-BPG concentration.

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e. fetal hemoglobin.

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All of the following statements regarding erythrocytes are true EXCEPT:

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a. Aged erythrocytes are removed by the liver, where the iron is recycled.

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b. Erythrocytes have a life span of approximately 120 days.

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c. Red blood cells generally lose their nuclei before entering the circulation.

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d. Reticulocytes are immature RBCs that still have a little RNA.

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e. Persons with anemia have a higher than normal reticulocyte:erythrocyte ratio.

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All of the following statements regarding oxidative hemolysis are true EXCEPT:

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a. Reactive oxygen species are commonly generated by RBC metabolism.

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b. Superoxide dismutase and ...

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