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Chapter 14. Toxic Responses of the Kidney

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The kidney is responsible for all of the following EXCEPT:

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a. synthesis of renin.

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b. acid–base balance.

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c. reabsorption of electrolytes.

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d. regulation of extracellular fluid.

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e. release of angiotensin.

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Which of the following does NOT contribute to filtrate formation in the nephron?

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a. capillary hydrostatic pressure.

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b. positive charge of glomerular capillary wall.

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c. hydraulic permeability of glomerular capillary wall.

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d. colloid oncotic pressure.

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e. size of filtration slits.

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Which of the following is NOT a characteristic of the loop of Henle?

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a. There is reabsorption of filtered Na+ and K+.

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b. Tubular fluid in the thin descending limb is iso-osmotic to the renal interstitium.

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c. Water is freely permeable in the thin ascending limb.

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d. Na+ and Cl are reabsorbed in the thin ascending limb.

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e. The thick ascending limb is impermeable to water.

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Although the kidneys constitute 0.5% of total body mass, approximately how much of the resting cardiac output do they receive?

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a. 0.5% to 1%.

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b. 5%.

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c. 10%.

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d. 20% to 25%.

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e. 50% to 60%.

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Which of the following is most likely to occur after a toxic insult to the kidney?

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a. GFR will decrease in the unaffected kidney.

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b. Tight-junction integrity will increase in the nephron.

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c. The unaffected cells will undergo atrophy and proliferation.

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d. Clinical tests will likely show normal renal function.

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e. Glomerulotubular balance is lost.

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Chronic renal failure does not typically result in:

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a. decrease in GFR of viable nephrons.

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b. glomerulosclerosis.

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c. tubular atrophy.

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d. increased glomerular pressures.

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e. altered capillary permeability.

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All of the following ...

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