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Chapter 17. Toxic Responses of the Ocular and Visual System

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In which of the following locations would one NOT find melanin?

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a. iris.

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b. ciliary body.

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c. retinal pigment epithelium (RPE).

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d. uveal tract.

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e. sclera.

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Systemic exposure to drugs and chemicals is most likely to target which of the following retinal sites?

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a. RPE and ganglion cell layer.

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b. optic nerve and inner plexiform layer.

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c. RPE and photoreceptors.

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d. photoreceptors and ganglion cell layer.

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e. inner plexiform layer and RPE.

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Which of the following structures is NOT part of the ocular fundus?

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a. retina.

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b. lens.

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c. choroid.

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d. sclera.

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e. optic nerve.

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Drugs and chemicals in systemic blood have better access to which of the following sites because of the presence of loose endothelial junctions at that location?

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a. retinal choroid.

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b. inner retina.

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c. optic nerve.

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d. iris.

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e. ciliary body.

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All of the following statements regarding ocular irritancy and toxicity are true EXCEPT:

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a. The Draize test involves instillation of a potentially toxic liquid or solid into the eye.

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b. The effect of the irritant in the Draize test is scored on a weighted scale for the cornea, iris, and conjunctiva.

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c. The Draize test usually uses one eye for testing and the other as a control.

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d. The Draize test has strong predictive value in humans.

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e. The cornea is evaluated for opacity and area of involvement in the Draize test.

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Which of the following statements regarding color vision deficits is FALSE?

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a. Inheritance of a blue–yellow color deficit is common.

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b. Bilateral deficits in the visual cortex can lead to color blindness.

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c. Disorders of the outer retina produce blue–yellow deficits.

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d. Drug and chemical exposure most commonly ...

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