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Chapter 28. Nanotoxicology

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Which of the following is not a nanoparticle?

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a. carbon nanotubes.

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b. bucky-ball.

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c. graphene.

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d. zinc nanorods.

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e. bacteria.

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Which of the following answers is not true regarding nanoparticles?

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a. NPs can originate from natural sources including forest fires, volcanoes, and viruses.

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b. NPs can originate from unintentional sources including internal combustion engines and electric motors.

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c. NPs can originate from unintentional sources including ferritin and magnetotactic bacteria.

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d. NPs can originate from intentional sources including carbon nanotubes and metal oxide nanoparticles.

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e. NPs can originate from natural, and intentional and unintentional anthropogenic sources.

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In contrast to larger particles >500 nm, nanoparticles

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a. are highly likely to enter the body by dermal absorption.

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b. are highly likely to enter the body through the respiratory tract.

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c. are unlikely to adsorb to protein or lipid.

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d. are efficiently removed from the lungs via mucociliary transport.

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e. are not likely to undergo uptake and transport in sensory neurons.

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Which of the following statements is NOT true?

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a. Nanomaterials may be classified by geometry and chemistry.

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b. Engineered nanomaterials include quantum dots, C-nanofiber array, and few-layer grapheme.

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c. Agglomerates include primary particles held together by weak van der Waals forces.

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d. Aggregates include primary particles held by strong chemical bonds.

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e. Hydrodynamic diameter is unimportant in particle interactions.

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Nanoparticles can exert toxicity by all of the following mechanisms except:

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a. damage to DNA and chromosomes.

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b. induction of oxidant stress.

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c. interference with biotransformation enzyme activities.

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d. activation of signaling pathways.

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e. release of toxic metal ions from internalized NPs.

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Biodistribution of nanoparticles may be influenced by

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a. physicochemical properties such as plasma protein and respiratory tract mucus.

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b. physicochemical properties such as surface size and chemistry.

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c. physicochemical ...

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