TY  - CHAP
M1  - Book, Section
TI  - VASCULAR PURPURA
A1  - Hillman, Robert S.
A1  - Ault, Kenneth A.
A1  - Leporrier, Michel
A1  - Rinder, Henry M.
PY  - 2016
T2  - Hematology in Clinical Practice, 5e
AB  - CASE  HISTORY  •  Part  1A  46-year-old  woman  presents  with  a  complaint  of  more  than  3  months  of  fatigue  and  dyspnea  on  exertion.  Her  history  is  notable  for  lifelong  recurring  epistaxis,  requiring  repeated  nasal  packing,  septal  dermoplasty,  and  laser  therapy.  Her  father  also  had  repeated  epistaxis;  he  died  at  age  60  from  a  brain  abscess.  Examination  is  notable  for  pallor  and  multiple  blue-red  lesions  involving  the  lips  and  fingers.  The  remainder  of  the  examination  is  benign  except  for  a  positive  test  for  occult  blood  in  the  stool.CBC:  Hemoglobin/hematocrit  -  7  g/dL/22%MCV  -  64  fL  MCH  -  24  pg  MCHC  -  24  g/dLRDW-CV  -  24%  WBC  count  -  6,500/μLPlatelet  count  -  410,000/μLSMEAR  MORPHOLOGYMicrocytic,  hypochromic  with  marked  aniso-  and  poikilocytosis,  polychromasia,  and  the  occasional  cigar-shaped  cell.  White  blood  cells  and  platelets  are  both  normal.Reticulocyte  count/index  -  1.3%/<1.0QuestionsHow  should  the  anemia  be  described  and  does  the  history  suggest  a  specific  etiology?What  additional  tests  should  be  ordered  to  confirm  the  cause  of  the  anemia?  
SN  - 
PB  - McGraw-Hill Medical
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessbiomedicalscience.mhmedical.com/content.aspx?aid=1127768159
ER  -