RT Book, Section
A1 Hilal-Dandan, Randa
A1 Brunton, Laurence L.
SR Print(0)
ID 1127554293
T1 Antiviral Agents (Nonretroviral)
T2 Goodman and Gilman's Manual of Pharmacology and Therapeutics, 2e
YR 2016
FD 2016
PB McGraw-Hill Education
PP New York, NY
SN 9780071769174
LK accessbiomedicalscience.mhmedical.com/content.aspx?aid=1127554293
RD 2024/04/18
AB Viruses  are  simple  microorganisms  that  consist  of  either  double-  or  single-stranded  DNA  or  RNA  enclosed  in  a  protein  coat  called  a  capsid.  Some  viruses  also  possess  a  lipid  envelope  derived  from  the  infected  host  cell,  which,  like  the  capsid,  may  contain  antigenic  glycoproteins.  Effective  antiviral  agents  inhibit  virus-specific  replicative  events  or  preferentially  inhibit  virus-directed  rather  than  host  cell–directed  nucleic  acid  or  protein  synthesis  (Table  58-1).  Host  cell  molecules  that  are  essential  to  viral  replication  also  offer  targets  for  intervention.  Figure  58-1  gives  a  schematic  diagram  of  the  replicative  cycle  of  typical  DNA  and  RNA  viruses.