RT Book, Section
A1 Dinarello, Charles A.
A1 Porat, Reuven
A2 Kasper, Dennis L.
A2 Fauci, Anthony S.
SR Print(0)
ID 1141405032
T1 FEVER
T2 Harrison's Infectious Diseases, 3e
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9781259835971
LK accessbiomedicalscience.mhmedical.com/content.aspx?aid=1141405032
RD 2024/04/19
AB Body  temperature  is  controlled  by  the  hypothalamus.  Neurons  in  both  the  preoptic  anterior  hypothalamus  and  the  posterior  hypothalamus  receive  two  kinds  of  signals:  one  from  peripheral  nerves  that  transmit  information  from  warmth/cold  receptors  in  the  skin  and  the  other  from  the  temperature  of  the  blood  bathing  the  region.  These  two  types  of  signals  are  integrated  by  the  thermoregulatory  center  of  the  hypothalamus  to  maintain  normal  temperature.  In  a  neutral  temperature  environment,  the  human  metabolic  rate  produces  more  heat  than  is  necessary  to  maintain  the  core  body  temperature  in  the  range  of  36.5–37.5°C  (97.7–99.5°F).