RT Book, Section
A1 Koroshetz, Walter J.
A1 Nath, Avindra
A2 Kasper, Dennis L.
A2 Fauci, Anthony S.
SR Print(0)
ID 1141406977
T1 CHRONIC AND RECURRENT MENINGITIS
T2 Harrison's Infectious Diseases, 3e
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9781259835971
LK accessbiomedicalscience.mhmedical.com/content.aspx?aid=1141406977
RD 2024/04/19
AB Chronic  inflammation  of  the  meninges  (pia,  arachnoid,  and  dura)  can  produce  profound  neurologic  disability  and  may  be  fatal  if  not  successfully  treated.  Chronic  meningitis  is  diagnosed  when  a  characteristic  neurologic  syndrome  exists  for  >4  weeks  and  is  associated  with  a  persistent  inflammatory  response  in  the  cerebrospinal  fluid  (CSF)  (white  blood  cell  count  >5/μL).  The  causes  are  varied,  and  appropriate  treatment  depends  on  identification  of  the  etiology.  Five  categories  of  disease  account  for  most  cases  of  chronic  meningitis:  (1)  meningeal  infections,  (2)  malignancy,  (3)  autoimmune  inflammatory  disorders,  (4)  chemical  meningitis,  and  (5)  parameningeal  infections.