RT Book, Section A1 Levin, Stephen A1 Lilis, Ruth A2 Wallace, Robert B. SR Print(0) ID 1141969051 T1 Silicosis T2 Maxcy-Rosenau-Last Public Health and Preventive Medicine, 15e YR 2017 FD 2017 PB McGraw-Hill Medical PP New York, NY SN 9780071441988 LK accessbiomedicalscience.mhmedical.com/content.aspx?aid=1141969051 RD 2024/04/20 AB Silicosis is a fibrotic lung disease produced by the inhalation of dust-containing free crystalline silicon dioxide (SiO2). Free silica and silicates represent a large part of the earth's crust. Silicon and oxygen are the two most important elements in the crust; about 27.7% of its composition is silicon, and 46.6% is oxygen. Free silica, the most widespread naturally occurring substance known to have a fibrogenic effect on the lungs, occurs in crystalline and amorphous forms. The crystalline forms that are fibrogenic are quartz, tridymite, and cristobalite; cryptocrystalline forms (consisting of minute crystals) are flint, chert, opal, and chalcedony. There are numerous forms of amorphous silica.