RT Book, Section A1 Wallace, Robert B. A2 Wallace, Robert B. SR Print(0) ID 1141973310 T1 Screening for Early and Asymptomatic Conditions T2 Maxcy-Rosenau-Last Public Health and Preventive Medicine, 15e YR 2017 FD 2017 PB McGraw-Hill Medical PP New York, NY SN 9780071441988 LK accessbiomedicalscience.mhmedical.com/content.aspx?aid=1141973310 RD 2024/04/24 AB The typical natural history of diseases and conditions dictates that at some point the biological onset of the disease occurs and progresses at varying rates until they become clinically evident. These rates may be as short as instantaneous, as in acute trauma, or could be life-long, as in a genetic risk factor for Alzheimer's disease. Primary prevention attempts to intercept the conditions that lead to disease onset, while secondary prevention generally relates to the early and asymptomatic detection of disease; that is, disease screening, in the hope that the trajectory toward clinical illness can be stopped or mitigated in a helpful way. When overt clinical illness is present, tertiary prevention refers to rehabilitative and other factors that deter disease progression and help return the patient to a healthier state.