RT Book, Section A1 Bauer, Douglas C. A1 McPhee, Stephen J. A2 Hammer, Gary D. A2 McPhee, Stephen J. SR Print(0) ID 1100863075 T1 Thyroid Disease T2 Pathophysiology of Disease: An Introduction to Clinical Medicine, 7e YR 2013 FD 2013 PB McGraw-Hill Education PP New York, NY SN 978-0-07-180600-8 LK accessbiomedicalscience.mhmedical.com/content.aspx?aid=1100863075 RD 2024/04/19 AB The thyroid gland synthesizes the hormones thyroxine (T4) and triiodothyronine (T3), iodine-containing amino acids that regulate the body’s metabolic rate. Adequate levels of thyroid hormone are necessary in infants for normal development of the CNS, in children for normal skeletal growth and maturation, and in adults for normal function of multiple organ systems. Thyroid dysfunction is one of the most common endocrine disorders encountered in clinical practice. Although abnormally high or low levels of thyroid hormones may be tolerated for long periods of time, usually there are symptoms and signs of overt thyroid dysfunction.