++
Chapter 7. Clinical Trials
++
++
++
What are the properties that classify research as a clinical trial?
++
++
++
A. A prospective experiment of an intervention with a control group that is conducted in humans
++
++
B. The retrospective analysis of data that was collected on humans exposed to a certain intervention
++
++
C. The testing of a new intervention on humans or animals
++
++
++
++
++
What type of design would allow one to study an interaction effect?
++
++
++
++
++
++
++
++
++
++
++
++
Why do we randomize trials?
++
++
++
A. To avoid selection bias
++
++
B. To ensure treatment assignment balance within a certain prognostic variable
++
++
C. To ensure valid statistical tests
++
++
++
++
++
What makes an ideal primary outcome?
++
++
++
A. One that can be easily dichotomized
++
++
B. One that is a short-term endpoint
++
++
C. One that is valid and reliable
++
++
++
++
++
What phase of clinical trial development assesses what dose to use?
++
++
++
++
++
++
++
++
++
++
++
++
Women are considered a vulnerable population.
++
++
++
++
++
++
++
++
++
++
++
A. a variable that impacts the outcome regardless of treatment.
++
++
B. something to be avoided in trials.
++
++
C. a variable that impacts the outcome because of treatment.
++
++
++
++
++
Sample size estimation is based on
++
++
++
++
++