Appendix A

Table A–1.Summary of major reabsorption and secretion events by major tubular segments

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Table A–1. Summary of major reabsorption and secretion events by major tubular segments

Proximal tubule

Loop of Henle

Distal tubule

Collecting ducts

Organic nutrients

Urea

Proteins, peptides

Phosphate

Sulfate

Organic anions^*

Organic cations^*

Urate

R (mostly) and S

Sodium

Chloride

Potassium

S (usually) and R

Water

Hydrogen ions

S or R

Bicarbonate

S or R

Ammonium

Calcium

^* Some passive transport may occur in the distal nephron depending on pH.

Table A–2Major functions of the various collecting-duct cells

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Table A–2 Major functions of the various collecting-duct cells

Principal cells

Reabsorb sodium
Secrete potassium
Reabsorb water

Type A intercalated cells

Secrete hydrogen ions
Reabsorb potassium

Type B intercalated cells

Secrete bicarbonate

Inner medullary cells

Reabsorb urea
Secrete ammonia/ammonium

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