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Appendix A

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Table A–1.Summary of major reabsorption and secretion events by major tubular segments
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Table A–1. Summary of major reabsorption and secretion events by major tubular segments
Proximal tubule Loop of Henle Distal tubule Collecting ducts

Organic nutrients

R

Urea

R

S

R

Proteins, peptides

R

Phosphate

R

Sulfate

R

Organic anions*

S

Organic cations*

S

Urate

R (mostly) and S

Sodium

R

R

R

R

Chloride

R

R

R

R

Potassium

R

R

S (usually) and R

Water

R

R

R

Hydrogen ions

S

S

S or R

Bicarbonate

R

R

S or R

Ammonium

S

R

S

Calcium

R

R

R

* Some passive transport may occur in the distal nephron depending on pH.

Table A–2Major functions of the various collecting-duct cells
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Table A–2 Major functions of the various collecting-duct cells

Principal cells

  1. Reabsorb sodium

  2. Secrete potassium

  3. Reabsorb water

Type A intercalated cells

  1. Secrete hydrogen ions

  2. Reabsorb potassium

Type B intercalated cells

  1. Secrete bicarbonate

Inner medullary cells

  1. Reabsorb urea

  2. Secrete ammonia/ammonium

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