Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content + Download Section PDF Listen ++Table Graphic Jump LocationTable B–1.Classes of diurecticsView Table||Download (.pdf) Table B–1. Classes of diurectics Class Mechanism Major site affected Carbonic anhydrase inhibitors Inhibit secretion of hydrogen ions, which reduces reabsorption of bicarbonate and sodium Proximal tubule Loop diuretics Inhibit Na-K-2Cl symporter in luminal membrane Thick ascending limb of Henle loop Thiazides Inhibit Na-Cl symporter in luminal membrane Distal convoluted tubule Potassium-sparing diuretics Inhibit action of aldosterone Block sodium channels Cortical collecting tubule Cortical collecting tubule