Editors
Renato D. Lopes, MD, MHS, PhD
Executive Director, Brazilian Clinical Research Institute
Federal University of São Paulo, São Paulo, Brazil
Associate Professor of Medicine, Division of Cardiology
Department of Medicine, Duke University Medical Center
Associate Program Director, Fellowship Program
Duke Clinical Research Institute
Durham, North Carolina
Robert A. Harrington, MD
Chair, Department of Medicine
Stanford University
Stanford, California
Contributors
Daniel K. Benjamin Jr., MD, PhD
Professor of Pediatrics, Duke University School of Medicine, Faculty Associate Director, Duke Clinical Research Institute, Durham, North Carolina
Chapter 1
Lisa G. Berdan, MHS, PA-C
Associate Director, Cardiovascular Megatrials, Duke Clinical Research Institute, Durham, North Carolina
Chapter 3
Robert Bigelow, PhD
Associate Director, Duke Clinical Research Institute, Durham, North Carolina
Chapter 5
Catherine Bodine, RN
Clinical Research Communications Specialist III, Duke Clinical Research Institute, Durham, North Carolina
Chapter 1
Anjan K. Chakrabarti, MD
Clinical Fellow in Medicine, Department of Medicine, Division of Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts
Chapter 2
Karen Chiswell, PhD
Senior Biostatistician, Duke Clinical Research Institute, Durham, North Carolina
Chapters 6 and 7
Michael Cohen-Wolkowiez, MD, PhD
Assistant Professor, Department of Pediatrics, Division of Infectious Disease, Duke Clinical Research Institute, Durham, North Carolina
Chapter 6
Lesley H. Curtis, PhD
Associate Professor in Medicine, Division of General Medicine, Department of Medicine, Duke University Medical Center, Durham, North Carolina
Kate Davis, RN
Clinical Research Communications Specialist III, Duke Clinical Research Institute, Durham, North Carolina
Chapter 1
Michaela A. Dinan, PhD
Biostatistician III, Clinical and Genetic Economics, Duke Clinical Research Institute, Durham, North Carolina
Chapter 10
Zubin J. Eapen, MD
Assistant Professor of Medicine, Division of Cardiology, Department of Medicine, Duke University Medical Center, Duke Clinical Research Institute, Durham, North Carolina
Chapter 16
C. Michael Gibson, MS, MD
Associate Professor of Medicine, Department of Medicine, Division of Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts
Chapter 2
Jeffrey T. Guptill, MD, MA
Medical Instructor, Division of Neurology, Department of Medicine, Duke University School of Medicine, Duke Clinical Research Institute, Durham, North Carolina
Chapter 7
Gail E. Hafley, MS
Senior Statistician, Duke Clinical Research Institute, Durham, North Carolina
Chapter 8
Bradley G. Hammill, MS
Senior Biostatistician, Clinical and Genetic Economics, Duke Clinical Research Institute, Durham, North Carolina
Chapter 12
Robert A. Harrington, MD
Chair, Department of Medicine, Stanford University, Stanford, California
Sergio Leonardi, MD
Research Scholar, Duke Clinical Research Institute, Durham, North Carolina
Chapter 8
Renato D. Lopes, MD, MHS, PhD
Executive Director, Brazilian Clinical Research Institute, Federal University of São Paulo, São Paulo, Brazil, Associate Professor of Medicine, Division of Cardiology, Department of Medicine, Duke University Medical Center, Associate Program Director, Fellowship Program, Duke Clinical Research Institute, Durham, North Carolina
Chapter 3
Karen S. Pieper, MS
Associate Director, Biostatistics, Duke Clinical Research Institute, Durham, North Carolina
Chapter 8
Craig J. Reist, PhD
Clinical Trials Project Leader III, Duke Clinical Research Institute, Durham, North Carolina
Chapter 3
Eric M. Reyes, PhD
Duke University Medical Center, Duke Clinical Research Institute, Durham, North Carolina
Chapter 15
Tyrus L. Rorick, RN
Clinical Trials Project Leader III, Duke Clinical Research Institute, Durham, North Carolina
Chapter 3
Kevin A. Schulman, MD
Professor of Medicine and Gregory Mario and Jeremy Mario Professor of Business Administration, Duke University, Associate Director, Health Services Research, Duke Clinical Research Institute, Durham, North Carolina
Chapter 4
Phillip J. Schulte, PhD
Duke University Medical Center, Duke Clinical Research Institute, Durham, North Carolina
Chapter 14
P. Brian Smith, MD, MHS, MPH
Chief, Division of Quantitative Sciences, Department of Pediatrics, Duke University Medical Center, Duke Clinical Research Institute, Durham, North Carolina
Chapter 9
Laine E. Thomas, PhD
Assistant Professor, Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, North Carolina
Chapters 14 and 15
Nidhi Tripathi, BS
Medical Student, Duke University School of Medicine, Durham, North Carolina
Chapter 1
Kevin N. Turner, MD
Clinical Fellow, Department of Pediatrics, University of North Carolina Medical Center, Chapel Hill, North Carolina
Chapter 9
David M. Vock, PhD
Division of Biostatistics, University of Minnesota School of Public Health, Minneapolis, Minnesota
Chapter 13
Kevin M. Watt, MD
Assistant Professor, Department of Pediatrics, Division of Critical Care Medicine, Duke University Medical Center, Duke Clinical Research Institute, Durham, North Carolina
Chapter 6
Yee Weng Wong, MBBS, FRACP
Research Scholar, Duke Clinical Research Institute, Durham, North Carolina
Chapter 4
Ying Xian, MD, PhD
Research Scholar, Duke Clinical Research Institute, Durham, North Carolina
Chapter 11