+
Arany
I, Megyesi
JK, Kaneto
H
et al Cisplatin-induced cell death is EGFR/src/ERK signaling dependent in mouse proximal tubule cells. Am J Physiol Renal Physiol. 2004;87:F543.
CrossRef +
Bach
PH The renal medulla and distal nephron toxicity. In: Sipes IG, McQueen CA, Gandolfi AJ, eds. Comprehensive toxicology. Vol 7. Oxford, UK: Elsevier; 1997:279–298.
+
Ballatori
N Mechanisms of metal transport across liver cell plasma membrane. Drug Metab Rev. 1991;23:83–132.
CrossRef
[PubMed: 1868779]
+
Basile
DP, Donohoe
D, Roethe
K, Osborn
JL Renal ischemic injury results in permanent damage to peritubular capillaries and influences long-term function. Am J Physiol Renal Physiol. 2001;281:F887–F899.
[PubMed: 11592947]
+
Bellomo
R, Ronco
C, Kellum
J
et al Acute renal failure—definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care. 2004;8(4):R204–R212.
CrossRef
[PubMed: 15312219]
+
Bernardo
JF, Branch
RA Amphotericin B. In: Sipes IG, McQueen CA, Gandolfi AJ, eds. Comprehensive Toxicology. Vol 7. Oxford, UK: Elsevier; 1997:475–494.
+
Bikbov
B, Perico
N, Abbate
M
et al The glomerulus: mechanisms of injury. In: McQueen CA, Schnellmann RG, eds. Comprehensive Toxicology. Vol 7. Oxford, UK: Elsevier; 2010:245–261.
+
Bonegio
R, Lieberthal
W Cisplatin-induced nephrotoxicity. In: Tarloff JB, Lash LH, eds. Toxicology of the Kidney. 3rd ed. Boca Raton, FL: CRC Press; 2005:779–815.
+
Brady
HR, Clarkson
W, Lieberthal
W Acute renal failure. In: Brenner BM, ed. Brenner and Rector’s The Kidney. 7th ed. Philadelphia: WB Saunders; 2004:1215–1292.
+
Brenner
BM, Bohrer
MP, Baylis
C, Deen
WM Determinants of glomerular permselectivity: insights derived from observations in vivo. Kidney Int. 1977;12:229–237.
CrossRef
[PubMed: 599834]
+
Brenner
BM, Meyer
TH, Hotstetter
TH Dietary protein intake and the progressive nature of kidney disease: the role of hemodynamically mediated glomerular injury in the pathogenesis of glomerular sclerosis in angina, renal ablation and intrinsic renal disease. N Engl J Med. 1982;307:652–659.
CrossRef
[PubMed: 7050706]
+
Brezis
M, Epstein
FH Pathophysiology of acute renal failure. In: Hook JB, Goldstein RS, eds. Toxicology of the Kidney. 2nd ed. New York: Raven Press; 1993:129–152.
+
Brezis
M, Rosen
S, Silva
P Transport activity modifies thick ascending limb damage in isolated perfused kidney. Kidney Int. 1984;25:65–72.
CrossRef
[PubMed: 6727130]
+
Bruschi
SA, West
K, Crabb
JW
et al Mitochondrial HSP60 (P1 protein) and a HSP-70 like protein (mortalin) are major targets for modification during
S-(1,1,2,2-tetrafluorethyl)-
l-cysteine induced nephrotoxicity. J Biol Chem. 1993;268:23157–23161.
[PubMed: 7901206]
+
Bucci
TJ, Howard
PC, Tolleson
WH
et al Renal effects of fumonisin mycotoxins in animals. Toxicol Pathol. 1998;26:160–164.
CrossRef
[PubMed: 9502399]
+
Burne
MJ, Daniels
F, El Ghandour
A
et al Identification of the CD4(+) T cell as a major pathogenic factor in ischemic acute renal failure. J Clin Invest. 2001;108:1065–1073.
CrossRef +
Burne-Taney
MJ, Ascon
DB, Daniels
F, Racusen
L, Baldwin
W, Rabb
H B cell deficiency confers protection from renal ischemia reperfusion injury. J Immunol. 2003;171:3210–3215.
CrossRef
[PubMed: 12960350]
+
Charney
D, Solez
K, Racusen
LC Nephrotoxicity of cyclosporine and other immunosuppressive and immunotherapeutic agents. In: Tarloff JB, Lash LH, eds. Toxicology of the Kidney. 3rd ed. Boca Raton, FL: CRC Press; 2005:687–777.
+
Chen
Q, Jone1s
TW, Brown
PC, Stevens
JL The mechanism of cysteine conjugate cytotoxicity in renal epithelial cells. J Biol Chem. 1990;265:21603–21611.
[PubMed: 2254317]
+
Chen
Q, Yu
K, Stevens
JL Regulation of the cellular stress response by reactive electrophiles: the role of covalent binding and cellular thiols in transcriptional activation of the 70-kDa heat shock protein gene by nephrotoxic cysteine conjugates. J Biol Chem. 1992;267:24322–24327.
[PubMed: 1447182]
+
Clifton
GG, Pearce
C, O’Neill
WM
Jr, Wallin
JD Early polyuria in the rat following single-dose
cis-dichlorodiammineplatinum (II): effects on plasma vasopressin concentration and posterior pituitary function. J Lab Clin Med. 1982;100:659–670.
[PubMed: 6890090]
+
Coen
M, Holmes
E, Lindon
JC, Nicholson
JK NMR-based metabolic profiling and metabonomic approaches to problems in molecular toxicology. Chem Res Toxicol. 2008;21(1):9–27.
CrossRef
[PubMed: 18171018]
+
Conner
EA, Fowler
BA Mechanisms of metal-induced nephrotoxicity. In: Hook JB, Goldstein RS, eds. Toxicology of the Kidney. 2nd ed. New York: Raven Press; 1993:437–457.
+
Counts
RS, Nowak
G, Wyatt
RD, Schnellmann
RG Nephrotoxicants inhibition of renal proximal tubule cell regeneration. Am J Physiol. 1995:269:F274–F281.
[PubMed: 7653601]
+
Courjault
F, Leroy
D, Coquery
I, Toutain
H Platinum complex-induced dysfunction of cultured renal proximal tubule cells. Arch Toxicol. 1993;67:338–346.
CrossRef
[PubMed: 8396390]
+
Daemen
MARC, van ‘tVeer
C, Denecker
G
et al Inhibition of apoptosis induced by ischemia-reperfusion prevents inflammation. J Clin Invest. 1999;104:541–549.
CrossRef
[PubMed: 10487768]
+
De Broe
ME Anagesic nephropathy. In: Tarloff JB, Lash LH, eds. Toxicology of the Kidney. 3rd ed. Boca Raton, FL: CRC Press; 2005:619–634.
+
Decker
B, Molitoris
BA Aminoglycoside-induced nephrotoxicity. In: McQueen CA, Schnellmann RG, eds. Comprehensive Toxicology. Vol 7. Oxford, UK: Elsevier; 2010:329–346.
+
Declercq
W, Vanden Berghe
T, Vandenabeele
P RIP kinases at the crossroads of cell death and survival. Cell. 2009;138(2):229–232.
CrossRef
[PubMed: 19632174]
+
Dekant
W Chemical-induced nephrotoxicity mediated by glutathione S-conjugate formation. In: Tarloff JB, Lash LH, eds. Toxicology of the Kidney. 3rd ed. Boca Raton, FL: CRC Press; 2005:995–1020.
+
Dickman
KG, Grollman
AP Nephrotoxicity of natural products: aristolochic acid and fungal toxins. In: McQueen CA, Schnellmann RG, eds. Comprehensive Toxicology. Vol 7. Oxford, UK: Elsevier; 2010: 433–458.
+
Dong
J, Ramachandiran
S, Tikoo
K, Jia
Z, Lauu
SS, Monks
TJ EGFR-independent activation of p38 MAPK and EGFR-dependent activation of ERK1/2 are required for ROS-induced renal cell death. Am J Physiol Renal Physiol. 2004;287:F1049–F1058.
CrossRef
[PubMed: 15226155]
+
Dunn
RB, Anderson
S, Brenner
B The hemodynamic basis of progressive renal disease. Semin Nephrol. 1986;6:122–138.
[PubMed: 3303239]
+
Eknoyan
G, Bulger
RE, Dobyan
DC Mercuric chloride-induced acute renal failure in the rat: I. Correlation of functional and morphologic changes and their modification by clonidine. Lab Invest. 1982;46:613–620.
[PubMed: 6211571]
+
Emeigh Hart
SGE, Wyand
DS, Khairallah
EA, Cohen
SD A role for the glutathione conjugate and renal cytochrome P450 in acetaminophen (APAP) induced nephrotoxicity in the CD-1 mouse. Toxicologist. 1990;11:57.
+
Emeigh Hart
SGE, Beierschmitt
WP, Wyand
DS
et al Acetaminophen nephrotoxicity in CD-1 Mice. I. Evidence of a role for in situ activation in selective covalent binding and toxicity. Toxicol Appl Pharmacol. 1994;126:267–275.
CrossRef
[PubMed: 8209379]
+
Filler
G, Bokenkamp
A, Hofmann
W, Le Bricon
T, Martinez-Bru
C, Grubb
A Cystatin C as a maker of GFR-history, indications and future research. Clin Biochem. 2005;38:1–8.
CrossRef
[PubMed: 15607309]
+
Fowler
BA Other nephrotoxic metals and nanometallic particles. In: McQueen CA, Schnellmann RG, eds. Comprehensive Toxicology. Vol 7. Oxford, UK: Elsevier; 2010:495–506.
+
Ford
SM In vitro toxicity systems. In: Sipes IG, McQueen CA, Gandolfi AJ, eds. Comprehensive Toxicology. Vol 7. Oxford, UK: Elsevier; 1997:121–142.
+
Ford
SM In vitro techniques in screening and mechanistic studies: cell culture, cell-free systems, and molecular and cell biology. In: Tarloff JB, Lash LH, eds. Toxicology of the Kidney. 3rd ed. Boca Raton, FL: CRC Press; 2005:191–213.
+
Francescato
HD, Costa
RS, Junior
FB, Coimbra
TM Effect of NK inhibition on cisplatin-induced renal damage. Nephrol Dial Transplant. 2007;22:2138–2148.
CrossRef
[PubMed: 17438009]
+
Fukino
H, Hirai
M, Hsueh
YM, Yamane
Y Effect of zinc pretreatment on mercuric chloride-induced lipid peroxidation in the rat kidney. Toxicol Appl Pharmacol. 1984;73:395–401.
CrossRef
[PubMed: 6232736]
+
Gil
FZ, Malnic
G Effect of amphotericin B on renal tubular acidification in the rat. Pflugers Arch. 1989;413:280–286.
CrossRef
[PubMed: 2717375]
+
Goering
PL, Fisher
BR, Chaudhary
PP, Dick
CA Relationship between stress protein induction in rat kidney by mercuric chloride and nephrotoxicity. Toxicol Appl Pharmacol. 1992;113:184–191.
CrossRef
[PubMed: 1561627]
+
Goering
PL, Fisher
BR, Noren
BT
et al Mercury induces regional and cell-specific stress protein expression in rat kidney. Toxicol Sci. 2000;53:447–457.
CrossRef
[PubMed: 10696793]
+
Goldstein
RS Biochemical heterogeneity and site-specific tubular injury. In: Hook JB, Goldstein RS, eds. Toxicology of the Kidney. 2nd ed. New York: Raven Press; 1993:201–248.
+
Goligorsky
MS, Patschan
D, Kuo
M-C
et al Cell adhesion molecules in renal injury. In: McQueen CA, Schnellmann RG, eds. Comprehensive Toxicology. Vol 7. Oxford, UK: Elsevier; 2010:213–244.
+
Gopee
NV, He
Q, Sharma
RP Fumonisin B1-induced apoptosis is associated with delayed inhibition of protein kinase C, nuclear factor-kappaB and tumor necrosis factor alpha in LLC-PK1 cells. Chem Biol Interact. 2003;146:131–145.
CrossRef
[PubMed: 14597127]
+
Groves
CE, Hayden
PJ, Lock
EA, Schnellmann
RG Differential cellular effects in the toxicity of haloalkene and haloalkane cysteine conjugates to rabbit renal proximal tubules. J Biochem Toxicol. 1993;8:49–56.
CrossRef
[PubMed: 8492303]
+
Groves
CE, Lock
EA, Schnellmann
RG The role of lipid peroxidation in renal proximal tubule cell death induced by haloalkene cysteine conjugates. J Toxicol Appl Pharmacol. 1991;107:54–62.
CrossRef +
Hallman
MA, Zhuang
S, Schnellmann
RG Regulation of dedifferentiation and redifferentiation in renal proximal tubular cells by the epidermal growth factor receptor. J Pharmacol Exp Ther. 2008;325(2):520–528.
CrossRef
[PubMed: 18270318]
+
Hammerman
MR, Miller
SB Therapeutic use of growth factors in renal failure. J Am Soc Nephrol. 1994;5:1–11.
[PubMed: 7948775]
+
Harriman
JF, Liu
XL, Aleo
MD, Machaca
K, Schnellmann
RG Endoplasmic reticulum Ca
2+ signaling and calpains mediate renal cell death. Cell Death Differ. 2002;9:734–741.
CrossRef
[PubMed: 12058278]
+
Hart
SE, Kinter
LB Assessing renal effects of toxicants in vivo. In: Tarloff JB, Lash LH, eds. Toxicology of the Kidney. 3rd ed. Boca Raton, FL: CRC Press; 2005:81–147.
+
Hart
SGE In vivo methodologies used to assess renal function and injury. In: McQueen CA, Schnellmann RG, eds. Comprehensive Toxicology. Vol 7. Oxford, UK: Elsevier; 2010:263–303.
+
Hayden
PJ, Stevens
JL Cysteine conjugate toxicity, metabolism and binding to macro-molecules in isolated rat kidney mitochondria. Mol Pharmacol. 1990;37:468–476.
[PubMed: 2314393]
+
Hayden
PJ, Welsh
CJ, Yang
Y
et al Formation of mitochondrial phospholipid adducts by nephrotoxic cysteine conjugate metabolites. Chem Res Toxicol. 1992;5:231–237.
+
Hayden
PJ, Yang
Y, Ward
AJ
et al Formation of diflourothionoacetyl-protein adducts by
S-(1,1,2,2-tetrafluoroethyl)-
l-cysteine metabolites: nucleophilic catalysis of stable lysyl adduct formation by histidine and tyrosine. Biochemistry. 1991;30:5935–5943.
CrossRef
[PubMed: 1904276]
+
Holmes
E, Cloarec
O, Nicholson
JK Probing latent biomarker signatures and in vivo pathway activity in experimental disease states via statistical total correlation spectroscopy (STOCSY) of biofluids: application to HgCl
2 toxicity. J Proteome Res. 2006;5:1313–1320.
CrossRef
[PubMed: 16739983]
+
Humphreys
BD, Czerniak
S, DiRocco
DP, Hasain
W, Cheema
R, Bonventre
JV Repair of injured proximal tubule does not involve specialized progenitors. Proc Natl Acad Sci U S A. 2011;108(22):9226–9231.
CrossRef
[PubMed: 21576461]
+
Humphreys
BD, Valerius
MT, Kibayashi
A
et al Intrinsic epithelial cells repair the kidney after injury. Cell Stem Cell. 2008;2(3):284–291.
CrossRef
[PubMed: 18371453]
+
Ikeda
M, Prachasilchai
W, Burner-Taney
MJ, Rabb
H, Yokota-Ikeda
N Ischemic acute tubular necrosis models and drug discovery: a focus on cellular inflammation. Drug Discov Today. 2006;11:364–370.
CrossRef
[PubMed: 16580979]
+
Jarnberg
P Renal toxicity of anesthetic agents. In: DeBroe ME, Porter GA, Bennett AM, Verpooten GA, eds. Clinical Nephrotoxicants, Renal Injury from Drugs and Chemicals. The Netherlands: Kluwer; 1998:413–418.
+
Kanwar
YS, Liu
ZZ, Kashihara
N, Wallner
EI Current status of the structural and functional basis of glomerular filtration and proteinuria. Semin Nephrol. 1991;11:390–413.
[PubMed: 1947494]
+
Kaushal
GP, Basnakian
AG, Shah
SV Apoptotic pathways in ischemic acute renal failure. Kidney Int. 2004;66(2):500–506.
CrossRef
[PubMed: 15253697]
+
Kaushal
GP, Singh
AB, Shah
SV Identification of gene family cf caspases in rat kidney and altered expression in ischemia-reperfusion injury. Am J Physiol. 1998;274:F587–F595.
[PubMed: 9530276]
+
Kelly
KJ Heat shock (stress response) proteins and renal ischemia/reperfusion injury. Contrib Nephrol. 2005;148:86–106.
[PubMed: 15912029]
+
Kido
T, Nordberg
G Cadmium-induced renal effects in the general environment. In: DeBroe ME, Porter GA, Bennett AM, Verpooten GA, eds. Clinical Nephrotoxicants, Renal Injury from Drugs and Chemicals. The Netherlands: Kluwer; 1998:345–362.
+
Kidwell
DT, KcKeown
JW, Grider
JS
et al Acute effects of gentamicin on thick ascending limb function in the rat. Eur J Pharmaco Environ Toxicol Pharmacol Section. 1994;270:97–103.
CrossRef +
Kinsey
GR, Li
L, Okusa
MD Inflammation in acute kidney injury. Nephron Exp Nephrol. 2008;109(4):e102–e107.
CrossRef
[PubMed: 18802372]
+
Kirkpatrick
DS, Gandolfi
AJ In vitro techniques in screening and mechanistic studies: organ perfusion, slices, and nephron components. In: Tarloff JB, Lash LH, eds. Toxicology of the Kidney. 3rd ed. Boca Raton, FL: CRC Press; 2005:149–189.
+
Klaassen
CD, Liu
J, Choudhuri
S Metallothionein: an intracellular protein to protect cadmium toxicity. Ann Rev Pharmacol Toxicol. 1999;39:267–294.
CrossRef +
Komatsuda
A, Wakui
H, Satoh
K
et al Altered localization of 73-kilodalton heat shock protein in rat kidneys with gentamicin–induced acute tubular injury. Lab Invest. 1993;68:687–695.
[PubMed: 8515655]
+
Koyner
JL, Murray
PT, Bakris
GK The pathogenesis and prevention of radiocontrast medium-induced renal dysfunction. In: McQueen CA, Schnellmann RG, eds. Comprehensive Toxicology. Vol 7. Oxford, UK: Elsevier; 2010:359–386.
+
Lanese
DM, Conger
JD Effects of endothelin receptor antagonist on cyclosporine-induced vasoconstriction in isolated rat renal arterioles. J Clin Invest. 1993;91:2144–2149.
CrossRef
[PubMed: 8486781]
+
Lash
LH, Cummings
BS Mechanisms of toxicant-induced acute kidney injury. In: McQueen CA, Schnellmann RG, eds. Comprehensive Toxicology. Vol 7. Oxford, UK: Elsevier; 2010:81–115.
+
Lauwerys
RR, Bernard
AM, Roels
HA, Buchet
JP Cadmium: exposure markers as predictors of nephrotoxic effects. Clin Chem. 1994;40:1391–1394.
[PubMed: 8013125]
+
Lehman-McKeeman
LD a2u-Globulin nephropathy. In: McQueen CA, Schnellmann RG eds. Comprehensive Toxicology. Vol 7. Oxford, England: Elsevier; 2010:507–521.
+
Lemasters
JJ, Qian
T, Bradham
CA
et al Mitochondrial dysfunction in the pathogenesis of necrotic and apoptotic cell death. J Bioenerg Biomembr. 1999;31:305–319.
CrossRef
[PubMed: 10665521]
+
Leonard
I, Zanen
J, Nonclercq
D
et al Modification of immunoreactive EGF and EGF receptor after acute tubular necrosis induced by tobramycin or cisplatin. Ren Fail. 1994;16(5):583–608.
CrossRef
[PubMed: 7855315]
+
Levin
S, Bucci
TJ, Cohen
SM
et al The nomenclature of cell death: recommendations of an
ad hoc committee of the society of toxicologic pathologists. Toxicol Pathol. 1999;27:484–490.
CrossRef
[PubMed: 10485836]
+
Lieberthal
W, Triaca
V, Levine
J Mechanisms of death induced by cisplatin in proximal tubular epithelial cells: apoptosis vs. necrosis. Am J Physiol. 1996;270:F700–F708.
[PubMed: 8967349]
+
Liu
X, Schnellmann
RG Calpain mediates progressive plasma membrane permeability and proteolysis of cytoskeleton-associated paxillin, talin, and vinculin during renal cell death. J Pharmacol Exp Ther. 2003;304:63–70.
CrossRef
[PubMed: 12490576]
+
Liu
X, Godwin
ML, Nowak
G Protein kinase C-alpha inhibits the repair of oxidative phosphorylation after S-(1,2-dichlorovinyl)-L-cysteine injury in renal cells. Am J Physiol Renal Physiol. 2004;287(1):F64–F73.
CrossRef
[PubMed: 14996667]
+
Lock
EA Renal xenobiotic metabolism. In: McQueen CA, Schnellmann RG, eds. Comprehensive Toxicology. Vol 7. Oxford, UK: Elsevier; 2010:55–79.
+
Lock
EA, Reed
CJ Renal xenobiotic metabolism. In: Sipes IG, McQueen CA, Gandolfi AJ, eds. Comprehensive Toxicology. Vol 7. Oxford, UK: Elsevier; 1997:77–98.
+
Lund
BO, Miller
DM, Woods
JS Studies in Hg(II)-induced H
2O
2 formation and oxidative stress in vivo and in vitro in rat kidney mitochondria. Biochem Pharmacol. 1993;45:2017–2024.
CrossRef
[PubMed: 8512585]
+
Maddox
DA, Brenner
BM Glomerular ultrafiltration. In: Brenner BM, Rector FC, eds. The Kidney. 4th ed. Philadelphia: WB Saunders; 1991:205–244.
+
Mehendale
HM Halogenated hydrocarbons. In: McQueen CA, Schnellmann RG, eds. Comprehensive Toxicology. Vol 7. Oxford, UK: Elsevier; 2010:459–474.
+
Mehta
RL, Kellum
JA, Shah
SV
et al Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care. 2007;11(2):R31.
CrossRef
[PubMed: 17331245]
+
Melnick
R An alternative hypothesis on the role of chemically induced protein droplet (α
2u-globulin) nephropathy in renal carcinogenesis. Regul Toxicol Pharmacol. 1992;16:111–125.
CrossRef
[PubMed: 1279759]
+
Miller
GW, Schnellmann
RG Cytoprotection by inhibition of chloride channels: the mechanism of action of glycine and strychnine. Life Sci. 1993;53:1211–1215.
CrossRef
[PubMed: 8412478]
+
Miller
GW, Schnellmann
RG Inhibitors of renal chloride transport do not block toxicant-induced chloride influx in the proximal tubule. Toxicol Lett. 1995;76:179–184.
CrossRef
[PubMed: 7725349]
+
Naesens
M, Kuypers
DR, Sarwal
M Calcineurin inhibitor nephrotoxicity. Clin J Am Soc Nephrol. 2009;4(2):481–508.
[PubMed: 19218475]
+
Nowak
G Protein kinase C-alpha and ERK1/2 mediate mitochondrial dysfunction, decreases in active Na
+ transport, and cisplatin-induced apoptosis in renal cells. J Biol Chem. 2002;277:43377–43388.
CrossRef
[PubMed: 12218054]
+
Nowak
G Protein kinase C mediates repair of mitochondrial and transport functions after toxicant-induced injury in renal cells. J Pharmacol Exp Ther. 2003;306:157–165.
CrossRef
[PubMed: 12665543]
+
Nowak
G, Bakajsova
D, Clifton
GL Protein kinase C-{
epsilon} modulates mitochondrial function and active Na
+ transport after oxidant injury in renal cells. Am J Physiol Renal Physiol. 2004;286:F307.
CrossRef
[PubMed: 14570699]
+
Nowak
G, Bakajsova
D, Samarel
AM Protein kinase C-{varepsilon} activation induces mitochondrial dysfunction and fragmentation in renal proximal tubules. Am J Physiol Renal Physiol. 2011;301:F197–F208.
CrossRef
[PubMed: 21289057]
+
Nowak
G, Clifton
GL, Godwin
ML, Bakajsova
D Activation of ERK1/2 pathway mediates oxidant-induced decreases in mitochondrial function in renal cells. Am J Physiol Renal Physiol. 2006;291:5840–5855.
CrossRef +
Okada
Y, Maeno
E, Shimizu
T, Manabe
K, Mori
S, Nabekura
T Dual roles of plasmalemmal chloride channels in induction of cell death. Pflugers Arch. 2004;448:287–295.
CrossRef
[PubMed: 15103464]
+
Pabla
N, Dong
Z Cisplatin nephrotoxicity: mechanisms and renprotective strategies. Kidney Int. 2008;73:994–1007.
CrossRef
[PubMed: 18272962]
+
Palmer
BF, Heinrich
WL Toxic nephropathy. In: Brenner BM, ed. Brenner and Rector’s The Kidney. 7th ed. Philadelphia: WB Saunders; 2004:1625–1658.
+
Rabb
H, Daniels
F, O’Donnell
M
et al Pathophysiological role of T lymphocytes in renal ischemia-reperfusion injury in mice. Am J Physiol. 2000;279:F525–F531.
+
Racusen
LC, Solez
K Nephrotoxicity of cyclosporine and other immunotherapeutic agents. In: Hook JB, Goldstein RS, eds. Toxicology of the Kidney. 2nd ed. New York: Raven Press; 1993:319–360.
+
Ramachandiran
S, Huang
Q, Dong
J, Lau
SS, Monks
TJ Mitogen-activated protein kinases contribute to reactive oxygen species-induced cell death in renal proximal tubule epithelial cells. Chem Res Toxicol. 2002;15:1635.
CrossRef
[PubMed: 12482247]
+
Rankin
GO, Valentovic
MA Role of xenobiotic metabolism. In: Tarloff JB, Lash LH, eds. Toxicology of the Kidney. 3rd ed. Boca Raton, FL: CRC Press; 2005:217–243.
+
Safirstein
R, Deray
G Anticancer, cisplatin/carboplatin. In: DeBroe ME, Porter GA, Bennett AM, Verpooten GA, eds. Clinical Nephrotoxicants, Renal Injury from Drugs and Chemicals. The Netherlands: Kluwer; 1998:261–272.
+
Sanchez-Gonzalez
PD, Lopez-Hernandez
FJ, Lopez-Novoa
JM, Morales
AI An integrative view of the pathophysiological events leading to cisplatin nephrotoxicity. Crit Rev Toxicol. 2011;41:803–821.
CrossRef
[PubMed: 21838551]
+
Schnellmann
RG Analgesic nephropathy in rodents. J Toxicol Environ Health, Part B. 1998;1:81–90.
CrossRef +
Schnellmann
RG, Cross
TJ, Lock
EA Pentachlorabutadienyl-
l-cysteine uncouples oxidative phosphorylation by dissipating the proton gradient. Toxicol Appl Pharmacol. 1989;100:498–505.
CrossRef
[PubMed: 2551076]
+
Schnellmann
RG, Griner
RD Mitochondrial mechanisms of tubular injury. In: Goldstein RS, ed. Mechanisms of Injury in Renal Disease and Toxicity. Boca Raton, FL: CRC Press; 1994:247–265.
+
Schnellmann
RG, Lock
EA, Mandel
LJ A mechanism of
S -(1,2,3,4,4- pentachloro-1,3-butadienyl)-
l-cysteine toxicity to rabbit renal proximal tubules. Toxicol Appl Pharmacol. 1987;90:513–521.
CrossRef
[PubMed: 3660416]
+
Servais
H, Mingeot-Leclercq
M-P, Tulkens
PM Antibiotic-induced nephrotoxicity. In: Tarloff JB, Lash LH, eds. Toxicology of the Kidney. 3rd ed. Boca Raton, FL: CRC Press; 2005:635–685.
+
Shaik
SP, Fifer
EK, Nowak
G Protein kinase B/Akt modulates nephrotoxicant-induced necrosis in renal cells. Am J Physiol Renal Physiol. 2007;292:F292–F303.
CrossRef
[PubMed: 16940564]
+
Shaik
SP, Fifer
EK, Nowak
G Akt activation improves oxidative phosphorylation in renal proximal tubular cells following nephrotoxicant injury. Am J Physiol Renal Physiol. 2008;294:F423–F432.
CrossRef
[PubMed: 18077599]
+
Sheikh-Hamad
D, Cacini
W, Buckley
AR
et al Cellular and molecular studies on cisplatin-induced apoptotic cell death in rat kidney. Arch Toxicol. 2004;78:147–155.
CrossRef
[PubMed: 14551673]
+
Shibutani
S, Dong
H, Suzuki
N
et al Selective toxicity of aristolochic acids I and II. Drug Metab Dispos. 2007;35(7):1217–1222.
CrossRef
[PubMed: 17392392]
+
Smith
JH, Maita
K, Sleight
SD, Hook
JB Effect of sex hormone status on chloroform nephrotoxicity and renal mixed function oxidases in mice. Toxicology. 1984;30:305–316.
CrossRef
[PubMed: 6729829]
+
Smith
MW, Ambudkar
IS, Phelps
PC
et al HgCl
2-induced changes in cytosolic Ca
2+ of cultured rabbit renal tubular cells. Biochem Biophys Acta. 1987;931:130–142.
CrossRef
[PubMed: 3663712]
+
Steinmetz
PR, Husted
RF Amphotericin B toxicity for epithelial cells. In: Porter GA, ed. Nephrotoxic Mechanisms of Drugs and Environmental Toxins. New York, London: Plenum Press; 1982:95–98.
+
Sweet
DH Renal organic cation and anion transport: from physiology to genes. In: McQueen CA, Schnellmann RG, eds. Comprehensive Toxicology. Vol 7. Oxford, UK: Elsevier; 2010:23–53.
+
Taal
MW, Chertow
GM, Marsden
PA, Skorecki
K, Yu
AS, Brenner
BM Brenner and Rector’s The Kidney. 9th ed. Elsevier Health Sciences; 2011.
+
Tarloff
JB Analgesics and nonsteroidal anti-inflammatory drugs. In: Sipes IG, McQueen CA, Gandolfi AJ, eds. Comprehensive Toxicology. Vol. 7. Oxford, UK: Elsevier; 1997:583–600.
+
Tarloff
JB Analgesics and nonsteroidal anti-inflammatory drugs. In: McQueen CA, Schnellmann RG, eds. Comprehensive Toxicology. Vol. 7. Oxford, UK: Elsevier; 2010:387–403.
+
Tarloff
JB, Kinter
LB In vivo methodologies used to assess renal function. In: Sipes IG, McQueen CA, Gandolfi AJ, eds. Comprehensive Toxicology. Vol. 7. Oxford, UK: Elsevier; 1997:99–120.
+
Townsend
DM, Hanigan
MH Inhibition of γ tglutamyl transpeptidase or cysteine S-conjugate β-lyase activity blocks the nephrotoxicity of cisplain in mice. J Pharmacol Exp Ther. 2002;300:142–148.
CrossRef
[PubMed: 11752109]
+
Ulozas
E Amphotericin B-induced nephrotoxicity. In: McQueen CA, Schnellmann RG, eds. Comprehensive Toxicology. Vol 7. Oxford, UK: Elsevier; 2010:347–357.
+
Vaidya
VS, Bonventre
JV, Ferguson
MA Biomarkers of acute kidney injury. In: McQueen CA, Schnellmann RG, eds. Comprehensive Toxicology. Vol 7. Oxford, UK: Elsevier; 2010:197–211.
+
van de Water
B, de Graauw
M, Le Devedec
S, Alderliesten
M Cellular stress responses and molecular mechanisms of nephrotoxicity. Toxicol Lett. 2006;162:83–93.
CrossRef
[PubMed: 16359832]
+
Vanherweghem
JL, Depierreux
M, Tielemans
C
et al Rapidly progressive interstitial renal fibrosis in young women: association with slimming regimen including Chinese herbs. Lancet. 1993;341(8842): 387–391.
CrossRef
[PubMed: 8094166]
+
Wallin
A, Jones
TW, Vercesi
AE
et al Toxicity of
S-pentachorobutadienyl-
l-cysteine studied with isolated rat renal cortical mitochondria. Arch Biochem Biophys. 1987;258:365–372.
CrossRef
[PubMed: 3674880]
+
Wang
C, Salahudeen
AK Cyclosporine nephrotoxicity: attenuation by an antioxidant-inhibitor of lipid peroxidation in vitro and in vivo. Transplantation. 1994;58:940–946.
CrossRef
[PubMed: 7940739]
+
Wang
C, Salahudeen
AK Lipid peroxidation accompanies cyclosporine nephrotoxicity: effects of vitamin E. Kidney Int. 1995;47:927–934.
CrossRef
[PubMed: 7752594]
+
Wang
Y, Bollard
ME, Nicholson
JK, Holmes
E Exploration of the direct metabolic effects of mercury II chloride on the kidney on Sprague-Dawley rats using high-resolution magic angle spinning 1H NMR spectroscopy of intact tissue and patter recognition. J Pharm Biomed Anal. 2006;40:375–381.
CrossRef
[PubMed: 16146678]
+
Wang
Z, Chen
JK, Moeckel
G, Harris
RC Importance of functional EGF receptors in recovery from acute nephrotoxic injury. J Am Soc Nephrol. 2003;14(12):3147–3154.
CrossRef
[PubMed: 14638913]
+
Waters
SL, Sarang
SS, Wang
KK, Schnellmann
RG Calpains mediate calcium and chloride influx during the late phase of cell injury. J Pharmacol Exp Ther. 1997a;283:1177–1184.
+
Waters
SL, Wong
JK, Schnellmann
RG Depletion of endoplasmic reticulum calcium stores protects against hypoxia- and mitochondrial inhibitor-induced cellular injury and death. Biochem Biophys Res Commun. 1997b;240:57–60.
CrossRef +
Weinberg
JM, Harding
PG, Humes
HD Mitochondrial bioenergetics during the initiation of mercuric chloride-induced renal injury: II. Functional alterations of renal cortical mitochondria isolated after mercuric chloride treatment. J Biol Chem. 1982a;257:68–74.
+
Weinberg
JM, Harding
PG, Humes
HD Mitochondrial bioenergetics during the initiation of mercuric chloride-induced renal injury: I. Direct effects of in vitro mercuric chloride on renal cortical mitochondrial function. J Biol Chem. 1982b;257:60–67.
+
Woo
KR, Shu
WP, Kong
L, Liu
BC Tumor necrosis factor mediates apoptosis via Ca
2+/Mg
2+ dependent endonuclease with protein kinase C as a possible mechanism for cytokine resistance in human renal carcinoma cells. J Urol. 1996;155:1779–1783.
CrossRef
[PubMed: 8627883]
+
Zalups
RK Renal toxicity of mercury. In: Sipes IG, McQueen CA, Gandolfi AJ, eds. Comprehensive Toxicology. Vol 7. Oxford, UK: Elsevier; 1997:633–652.
+
Zalups
RK Renal handling and toxicity of mercury. In: McQueen CA, Schnellmann RG, eds. Comprehensive Toxicology. Vol 7. Oxford, UK: Elsevier; 2010:475–493.
+
Zalups
RK, Diamond
GL Nephrotoxicology of metal. In: Tarloff JB, Lash LH, eds. Toxicology of the Kidney. 3rd ed. Boca Raton, FL: CRC Press; 2005:937–994.
+
Zalups
RK, Lash
LH Advances in understanding the renal transport and toxicity of mercury. J Toxicol Environ Health. 1994;42:1–44.
CrossRef
[PubMed: 8169994]
+
Zhuang
S, Dang
Y, Schnellmann
RG Requirement of the epidermal growth factor receptor in renal epithelial cell proliferation and migration. Am J Physiol Renal Physiol. 2004;287(3):F365–F372.
CrossRef
[PubMed: 15213065]
+
Zhuang
S, Yan
Y, Han
J, Schnellmann
RG p38 kinase-mediated transactivation of the epidermal growth factor receptor is required for dedifferentiation of renal epithelial cells after oxidant injury. J Biol Chem. 2005;280(22):21036–21042.
CrossRef
[PubMed: 15797859]
+
Zhuang
S, Yan
Y, Daubert
RA, Han
J, Schnellmann
RG ERK promotes hydrogen peroxide-induced apoptosis through caspase-3 activation and inhibition of Akt in renal epithelial cells. Am J Physiol Renal Physiol. 2007;292:F440–F447.
CrossRef
[PubMed: 16885155]
+
Zhuang
S, Kinsey
GR, Yan
Y, Han
J, Schnellmann
RG Extracellular signal-regulated kinase activation mediates mitochondrial dysfunction and necrosis induced by hydrogen peroxide in renal proximal tubular cells. J Pharmacol Exp Ther. 2008;325(3):732–740.
CrossRef
[PubMed: 18339970]