TY - CHAP M1 - Book, Section TI - Neurotransmission and the Central Nervous System A1 - Molinoff, Perry B. A2 - Brunton, Laurence L. A2 - Chabner, Bruce A. A2 - Knollmann, Björn C. PY - 2015 T2 - Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 12e AB - Drugs that act in the central nervous system (CNS) are invaluable therapeutically. They can, e.g., relieve pain, reduce fever, suppress disordered movements, induce sleep or arousal, reduce appetite, and allay the tendency to vomit. Selectively acting drugs can be used to treat anxiety, depression, mania, or schizophrenia and do so without altering consciousness (Chapters 15 and 16). Socially acceptable stimulants and anti-anxiety agents contribute to emotional stability, relief of anxiety, and pleasure. However, the excessive use of such drugs can affect lives adversely when uncontrolled, self-administration leads to physical dependence or to toxic side effects (Chapter 24). The nonmedical self-administration of CNS-active drugs— recreational pharmacology—is widespread. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2023/09/22 UR - accessbiomedicalscience.mhmedical.com/content.aspx?aid=1127865986 ER -