TY - CHAP M1 - Book, Section TI - HEMOGLOBINOPATHIES A1 - Hillman, Robert S. A1 - Ault, Kenneth A. A1 - Leporrier, Michel A1 - Rinder, Henry M. PY - 2016 T2 - Hematology in Clinical Practice, 5e AB - CASE HISTORY • Part 1A 22-year-old African American woman presents to her obstetrician for prenatal care. She reports that she has been anemic since childhood but is unclear as to what kind of anemia. Past medical history is positive for splenectomy following blunt trauma to the abdomen in a car accident at age 16. Otherwise review of systems negative. A routine CBC shows the following results:CBC: Hematocrit/hemoglobin - 33%/11 g/dL (IU - 110 g/L)MCV - 75 fL MCH - 28 pg MCHC - 30 g/dLRDW-CV - 16%WBC count - 7,400/μLPlatelet count - 245,000/μLSMEAR MORPHOLOGYFindings on the blood smear include microcytosis, targeting, sickle cell forms, and both the occasional nucleated red blood cell (not shown) and red cells with Howell-Jolly bodies (also not shown).Reticulocyte count - 4.5%/3.0 Index - 1.5–2QuestionsHow should this anemia be described/categorized?Do the smear abnormalities indicate a specific abnormality?What additional tests should be ordered? SN - PB - McGraw-Hill Medical CY - New York, NY Y2 - 2024/03/29 UR - accessbiomedicalscience.mhmedical.com/content.aspx?aid=1127765786 ER -