TY - CHAP M1 - Book, Section TI - Paraneoplastic Neurologic Syndromes and Autoimmune Encephalitis A1 - Dalmau, Josep A1 - Rosenfeld, Myrna R. A2 - Longo, Dan L. PY - 2016 T2 - Harrison's Hematology and Oncology, 3e AB - Paraneoplastic neurologic disorders (PNDs) are cancer-related syndromes that can affect any part of the nervous system (Table 55-1). They are caused by mechanisms other than metastasis or by any of the complications of cancer such as coagulopathy, stroke, metabolic and nutritional conditions, infections, and side effects of cancer therapy. In 60% of patients, the neurologic symptoms precede the cancer diagnosis. Clinically disabling PNDs occur in 0.5–1% of all cancer patients, but they affect 2–3% of patients with neuroblastoma or small-cell lung cancer (SCLC) and 30–50% of patients with thymoma or sclerotic myeloma. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessbiomedicalscience.mhmedical.com/content.aspx?aid=1135230592 ER -