TY - CHAP M1 - Book, Section TI - INFECTIVE ENDOCARDITIS A1 - Karchmer, Adolf W. A2 - Kasper, Dennis L. A2 - Fauci, Anthony S. PY - 2017 T2 - Harrison's Infectious Diseases, 3e AB - The prototypic lesion of infective endocarditis, the vegetation(Fig. 24-1), is a mass of platelets, fibrin, microcolonies of microorganisms, and scant inflammatory cells. Infection most commonly involves heart valves but may also occur on the low-pressure side of a ventricular septal defect, on mural endocardium damaged by aberrant jets of blood or foreign bodies, or on intracardiac devices themselves. The analogous process involving arteriovenous shunts, arterio-arterial shunts (patent ductus arteriosus), or a coarctation of the aorta is called infective endarteritis. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessbiomedicalscience.mhmedical.com/content.aspx?aid=1141405951 ER -