TY - CHAP M1 - Book, Section TI - TETANUS A1 - Thwaites, C. Louise A1 - Yen, Lam Minh A2 - Kasper, Dennis L. A2 - Fauci, Anthony S. PY - 2017 T2 - Harrison's Infectious Diseases, 3e AB - Tetanus is an acute disease manifested by skeletal muscle spasm and autonomic nervous system disturbance. It is caused by a powerful neurotoxin produced by the bacterium Clostridium tetani and is completely preventable by vaccination. C. tetani is found throughout the world, and tetanus commonly occurs where the vaccination coverage rate is low. In developed countries, the disease is seen occasionally in individuals who are incompletely vaccinated. In any setting, established tetanus is a severe disease with a high mortality rate. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessbiomedicalscience.mhmedical.com/content.aspx?aid=1141407800 ER -