TY - CHAP M1 - Book, Section TI - Screening for Early and Asymptomatic Conditions A1 - Wallace, Robert B. A2 - Wallace, Robert B. PY - 2017 T2 - Maxcy-Rosenau-Last Public Health and Preventive Medicine, 15e AB - The typical natural history of diseases and conditions dictates that at some point the biological onset of the disease occurs and progresses at varying rates until they become clinically evident. These rates may be as short as instantaneous, as in acute trauma, or could be life-long, as in a genetic risk factor for Alzheimer's disease. Primary prevention attempts to intercept the conditions that lead to disease onset, while secondary prevention generally relates to the early and asymptomatic detection of disease; that is, disease screening, in the hope that the trajectory toward clinical illness can be stopped or mitigated in a helpful way. When overt clinical illness is present, tertiary prevention refers to rehabilitative and other factors that deter disease progression and help return the patient to a healthier state. SN - PB - McGraw-Hill Medical CY - New York, NY Y2 - 2024/03/29 UR - accessbiomedicalscience.mhmedical.com/content.aspx?aid=1141973310 ER -