TY - CHAP M1 - Book, Section TI - Genetic Toxicology A1 - Klapacz, Joanna A1 - Gollapudi, B. Bhaskar A2 - Klaassen, Curtis D. A2 - Watkins, John B. PY - 2021 T2 - Casarett & Doull’s Essentials of Toxicology, 4e AB - KEY POINTSGenetic toxicology assesses the effects of chemical and physical agents on the hereditary material (DNA) and on the genetic processes of living cells.Oncogenes are genes that stimulate the transformation of normal cells into cancer cells.Genetic toxicology assays serve to identify mutagens for purposes of hazard identification, and to characterize dose–response relationships and mutagenic mechanisms.A broad range of short-term assays for genetic toxicology serve to identify many mutagens and address the relationship between mutagens and cancer-causing agents. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/03/29 UR - accessbiomedicalscience.mhmedical.com/content.aspx?aid=1178013944 ER -