TY  - CHAP
M1  - Book, Section
TI  - Anticancer Chemotherapy, Pharmacology, and Mechanisms of Resistance
A1  - Chen, Eric
A1  - Tannock, Ian F.
A2  - Harrington, Lea A.
A2  - Tannock, Ian F.
A2  - Hill, Richard P.
A2  - Cescon, David W.
PY  - 2021
T2  - The Basic Science of Oncology, 6e
AB  - Although  most  new  drugs  for  cancer  are  agents  that  target  molecular  changes  that  occur  in  tumors  (described  in  Chap.  19),  chemotherapy  still  provides  the  backbone  of  drug  therapy  for  most  types  of  cancer.  Chemotherapy  is  used  commonly  to  treat  people  with  metastatic  cancer,  and  for  many  common  types  of  adult  cancer  can  provide  palliation—either  by  prolonging  survival  and/or  by  improving  quality  of  life.  Only  for  relatively  rare  tumors  such  as  childhood  leukemia  and  some  other  cancers  affecting  children,  and  testicular  cancer  in  men,  can  chemotherapy  cure  metastatic  disease.  Chemotherapy  (and  other  systemic  treatments)  are  also  used  either  before  (neoadjuvant)  or  after  (adjuvant)  surgery  (and  sometimes  before,  with,  or  after  radiotherapy)  in  people  without  overt  spread  of  disease,  and  can  then  improve  the  probability  of  cure  by  eliminating  undetectable  micrometastases.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/20
UR  - accessbiomedicalscience.mhmedical.com/content.aspx?aid=1179325526
ER  -