TY - CHAP M1 - Book, Section TI - Disorders of Mood and Anxiety A1 - Kandel, Eric R. A1 - Koester, John D. A1 - Mack, Sarah H. A1 - Siegelbaum, Steven A. PY - 2021 T2 - Principles of Neural Science, 6e AB - DEPRESSION, BIPOLAR DISORDER, AND ANXIETY DISORDERS have been well documented in medical writings since ancient times. In the fifth century BC, Hippocrates taught that moods depended on the balance of four humors—blood, phlegm, yellow bile, and black bile. An excess of black bile (melancholia is the ancient Greek term for black bile) was believed to cause a state dominated by fear and despondency. Robert Burton’s Anatomy of Melancholy (1621) was not only an important medical text but also viewed literature and the arts through the lens of melancholia. Such texts describe symptoms that remain familiar today; they also recognized that symptoms of depression and of anxiety often occur together. SN - PB - McGraw Hill CY - New York, NY Y2 - 2022/05/26 UR - accessbiomedicalscience.mhmedical.com/content.aspx?aid=1180646867 ER -