TY - CHAP M1 - Book, Section TI - Pain A1 - Kandel, Eric R. A1 - Koester, John D. A1 - Mack, Sarah H. A1 - Siegelbaum, Steven A. PY - 2021 T2 - Principles of Neural Science, 6e AB - ACCORDING TO THE INTERNATIONAL ASSOCIATION for the Study of Pain, pain is an unpleasant sensation and emotional experience associated with actual or potential tissue damage, or described in terms of such damage. Pricking, burning, aching, stinging, and soreness are among the most distinctive of all the sensory modalities. As with the other somatosensory modalities—touch, pressure, and position sense—pain serves an important protective function, alerting us to injuries that require evasion or treatment. In children born with insensitivity to pain, severe injuries often go unnoticed and can lead to permanent tissue damage. Yet pain is unlike other somatosensory modalities, or vision, hearing, and smell, in that it has an urgent and primitive quality, possessing a powerful emotional component. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/03/28 UR - accessbiomedicalscience.mhmedical.com/content.aspx?aid=1192995507 ER -