TY - CHAP M1 - Book, Section TI - Drug Therapy of Depression and Anxiety Disorders A1 - O'Donnell, James M. A1 - Shelton, Richard C. A2 - Brunton, Laurence L. A2 - Chabner, Bruce A. A2 - Knollmann, Björn C. Y1 - 2015 N1 - T2 - Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 12e AB - Depression and anxiety disorders are the most common mental illnesses, each affecting in excess of 10-15% of the population at some time in their lives. Both anxiety and depressive disorders are amenable to pharmacological treatments that have been developed since the 1950s. With the discovery of more selective and safer drugs, the use of antidepressants and anxiolytics has moved from the domain of psychiatry to other medical specialties, including primary care. The relative safety of the majority of commonly used antidepressants and anxiolytics notwithstanding, their optimal use requires a clear understanding of their mechanisms of action, pharmacokinetics, potential drug interactions, and the differential diagnosis of psychiatric illnesses. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2023/09/24 UR - accessbiomedicalscience.mhmedical.com/content.aspx?aid=1127866026 ER -