TY  - CHAP
M1  - Book, Section
TI  - Opioids, Analgesia, and Pain Management
A1  - Yaksh, Tony L.
A1  - Wallace, Mark S.
A2  - Brunton, Laurence L.
A2  - Chabner, Bruce A.
A2  - Knollmann, Björn C.
Y1  - 2015
N1  - 
T2  - Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 12e
AB  - Pain  is  a  component  of  virtually  all  clinical  pathologies,  and  management  of  pain  is  a  primary  clinical  imperative.  Opioids  are  a  mainstay  of  pain  treatment,  but  rational  therapy  may  involve,  depending  upon  the  pain  state,  one  or  more  drug  classes,  such  as  NSAIDs,  anticonvulsants,  and  antidepressants.  The  properties  of  these  non-opioid  agents  are  presented  in  Chapters  34,  21,  15.  This  chapter  focuses  first  on  the  biochemical,  pharmacological,  and  functional  nature  of  the  opioid  system  that  defines  the  effects  of  opioids  on  pain  processing,  gastrointestinal-endocrine-autonomic  functions,  and  reward-addiction  circuits.  Subsequently,  the  chapter  presents  principles  that  guide  the  use  of  opioid  and  non-opioid  agents  in  the  management  of  clinical  pain  states.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2023/06/07
UR  - accessbiomedicalscience.mhmedical.com/content.aspx?aid=1127866386
ER  -