TY - CHAP M1 - Book, Section TI - Imaging in Oncology A1 - Jaffray, David A. A2 - Tannock, Ian F. A2 - Hill, Richard P. A2 - Bristow, Robert G. A2 - Harrington, Lea Y1 - 2016 N1 - T2 - The Basic Science of Oncology, 5e AB - The need to detect and characterize cancer in an individual has resulted in a dramatic increase in the use of imaging over the last 20 years. Clinical imaging is now a routine part of diagnosis, staging, guiding localized therapy, and assessing response to treatment. Cancers occur anatomically among surrounding normal tissues, including critical structures, such as major vessels and nerves, and delineation of the extent of malignant and nonmalignant tissues is essential for planning surgery and radiation therapy. Cancers also have morphological, physiological, and biochemical heterogeneity (see Chaps. 10 and 12), which is important in understanding their biology and response to treatment. The ability to explore and define this heterogeneity with modern imaging methods, as well as serum and tissue-derived metrics, will enable "personalized cancer medicine." SN - PB - McGraw-Hill Education Medical CY - New York, NY Y2 - 2024/03/29 UR - accessbiomedicalscience.mhmedical.com/content.aspx?aid=1127472757 ER -