TY - CHAP M1 - Book, Section TI - Testicular Cancer A1 - Motzer, Robert J. A1 - Feldman, Darren R. A1 - Bosl, George J. A2 - Jameson, J. Larry Y1 - 2017 N1 - T2 - Harrison's Endocrinology, 4e AB - Primary germ cell tumors (GCTs) of the testis arising by the malignant transformation of primordial germ cells constitute 95% of all testicular neoplasms. Infrequently, GCTs arise from an extragonadal site, including the mediastinum, retroperitoneum, and, very rarely, the pineal gland. This disease is notable for the young age of the afflicted patients, the totipotent capacity for differentiation of the tumor cells, and its curability; approximately 95% of newly diagnosed patients are cured. Experience in the management of GCTs leads to improved outcome. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessbiomedicalscience.mhmedical.com/content.aspx?aid=1141274940 ER -