TY  - CHAP
M1  - Book, Section
TI  - LYME BORRELIOSIS
A1  - Steere, Allen C.
A2  - Kasper, Dennis L.
A2  - Fauci, Anthony S.
Y1  - 2017
N1  - 
T2  - Harrison's Infectious Diseases, 3e
AB  - Lyme  borreliosis  is  caused  by  a  spirochete,  Borrelia  burgdorferisensu  lato,  that  is  transmitted  by  ticks  of  the  Ixodes  ricinus  complex.  The  infection  usually  begins  with  a  characteristic  expanding  skin  lesion,  erythema  migrans  (EM;  stage  1,  localized  infection).  After  several  days  or  weeks,  the  spirochete  may  spread  to  many  different  sites  (stage  2,  disseminated  infection).  Possible  manifestations  of  disseminated  infection  include  secondary  annular  skin  lesions,  meningitis,  cranial  neuritis,  radiculoneuritis,  peripheral  neuritis,  carditis,  atrioventricular  nodal  block,  or  migratory  musculoskeletal  pain.  Months  or  years  later  (usually  after  periods  of  latent  infection),  intermittent  or  persistent  arthritis,  chronic  encephalopathy  or  polyneuropathy,  or  acrodermatitis  may  develop  (stage  3,  persistent  infection).  Most  patients  experience  early  symptoms  of  the  illness  during  the  summer,  but  the  infection  may  not  become  symptomatic  until  it  progresses  to  stage  2  or  3.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/24
UR  - accessbiomedicalscience.mhmedical.com/content.aspx?aid=1141410066
ER  -