TY - CHAP M1 - Book, Section TI - Respiratory Disease Prevention A1 - Coultas, David B. A1 - Samet, Jonathan M. A2 - Wallace, Robert B. Y1 - 2017 N1 - T2 - Maxcy-Rosenau-Last Public Health and Preventive Medicine, 15e AB - Diseases of the respiratory system are an important public health problem in all countries. The respiratory system, which includes the lungs and the upper airway that joins the trachea to the larynx, is exposed to a wide range of potentially injurious agents (Table 65-1). On average, an adult inhales about 5 L of air per minute; with exercise, the amount may increase 20-fold or more. With 10,000–20,000 L of air inhaled daily, agents present even in low concentrations may be toxic. The respiratory system is equipped with a remarkably effective system of defense mechanisms against inhaled particles and gases. Disease may result, however, if an acute exposure overwhelms the defenses (e.g., toxic gas inhalation), if an agent is particularly toxic even at low concentrations (e.g., toluene diisocyanate), if exposure is sustained (e.g., cigarette smoking), or if the exposed person is particularly susceptible (e.g., asthmatics). SN - PB - McGraw-Hill Medical CY - New York, NY Y2 - 2024/04/19 UR - accessbiomedicalscience.mhmedical.com/content.aspx?aid=1141961249 ER -