TY - CHAP M1 - Book, Section TI - Polychlorinated Dioxins and Polychlorinated Dibenzofurans A1 - Masuda, Yoshito A1 - Schecter, Arnold J. A2 - Wallace, Robert B. Y1 - 2017 N1 - T2 - Maxcy-Rosenau-Last Public Health and Preventive Medicine, 15e AB - Polychlorinated dibenzo-p-dioxins (PCDDs) have been described as the most toxic man-made chemicals known. They are synthetic, lipophilic, and very persistent. They are also relatively controversial. Toxicological studies of 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD), which is known as the most toxic congener among PCDDs and usually called Dioxin, demonstrate dose-dependent toxic responses to other PCDDs and related chemicals such as the polychlorinated dibenzofurans (PCDFs), which frequently accompany polychlorinated biphenyls (PCBs). (Both PCDFs and PCBs are chemically and biologically similar to PCDDs.) However, the findings from human studies, at least until recently, have been less consistent. SN - PB - McGraw-Hill Medical CY - New York, NY Y2 - 2024/04/19 UR - accessbiomedicalscience.mhmedical.com/content.aspx?aid=1141969902 ER -