TY - CHAP M1 - Book, Section TI - Toxic Responses of the Nervous System A1 - Moser, Virginia C. A1 - Aschner, Michael A1 - Richardson, Jason R. A1 - Bowman, Aaron B. A1 - Richardson, Rudy J. A2 - Klaassen, Curtis D. Y1 - 2019 N1 - T2 - Casarett & Doull’s Toxicology: The Basic Science of Poisons, 9th edition AB - Neurotoxicants and neurotoxins have been extensively studied because of their toxic effects on humans and their utility in the study of the nervous system (NS). Many insights into the organization and function of the NS are based on observations derived from the action of neurotoxicants. The binding of exogenous compounds to membranes has been the basis for the definition of specific receptors within the brain; an understanding of the roles of different cell types in the function of the NS has stemmed from the selectivity of certain toxicants in injuring specific cell types while sparing others, and important differences in basic metabolic requirements of different subpopulations of neurons have been inferred from the effects of neurotoxicants. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accessbiomedicalscience.mhmedical.com/content.aspx?aid=1158499879 ER -