TY  - CHAP
M1  - Book, Section
TI  - Biotransformation of Xenobiotics
A1  - Parkinson, Andrew
A1  - Ogilvie, Brian W.
A1  - Buckley, David B.
A1  - Kazmi, Faraz
A1  - Czerwinski, Maciej
A1  - Parkinson, Oliver
Y1  - 2012
N1  - 
T2  - Casarett and Doull's Toxicology: The Basic Science of Poisons, 8e
AB  - IntroductionPrinciples  of  Xenobiotic  BiotransformationHydrolysis,  Reduction,  and  OxidationHydrolysisCarboxylesterasesCholinesterases  (AChE  and  BChE)Paraoxonases  (Lactonases)Prodrugs  and  Alkaline  PhosphatasePeptidasesβ-GlucuronidaseEpoxide  HydrolasesReductionAzo-  and  Nitro-ReductionCarbonyl  Reduction—AKRs  and  SDRsDisulfide  ReductionSulfoxide  and  N-Oxide  ReductionQuinone  Reduction—NQO1  and  NQO2Dihydropyrimidine  DehydrogenaseDehalogenationDehydroxylation—mARC,  Cytochrome  b5,  b5Reductase,  and  Aldehyde  OxidaseAldehyde  Oxidase—Reductive  ReactionsOxidationAlcohol,  Aldehyde,  Ketone  Oxidation–Reduction  SystemsAlcohol  DehydrogenaseAldehyde  DehydrogenaseDimeric  Dihydrodiol  DehydrogenaseMolybdenum  Hydroxylases  (Molybdoenzymes)Xanthine  OxidoreductaseAldehyde  OxidaseAmine  OxidasesAromatizationPeroxidase-Dependent  CooxidationFlavin  MonooxygenasesCytochrome  P450Activation  of  Xenobiotics  byCytochrome  P450Inhibition  of  Cytochrome  P450Induction  of  Cytochrome  P450—XenosensorsConjugationGlucuronidation  and  Formationof  Acyl-CoA  ThioestersSulfonationMethylationAcetylationAmino  Acid  ConjugationGlutathione  ConjugationThiosulfate  Sulfurtransferase  (Rhodanese)Unusual  Conjugation  ReactionsPhosphorylation  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/18
UR  - accessbiomedicalscience.mhmedical.com/content.aspx?aid=1100085332
ER  -