TY - CHAP M1 - Book, Section TI - Transmitter Release Y1 - 2014 N1 - T2 - Principles of Neural Science, Fifth Edition AB - Transmitter Release Is Regulated by Depolarization of the Presynaptic TerminalRelease Is Triggered by Calcium InfluxThe Relation Between Presynaptic Calcium Concentration and ReleaseSeveral Classes of Calcium Channels Mediate Transmitter ReleaseTransmitter Is Released in Quantal UnitsTransmitter Is Stored and Released by Synaptic VesiclesSynaptic Vesicles Discharge Transmitter by Exocytosis and Are Recycled by EndocytosisCapacitance Measurements Provide Insight into the Kinetics of Exocytosis and EndocytosisExocytosis Involves the Formation of a Temporary Fusion PoreThe Synaptic Vesicle Cycle Involves Several StepsExocytosis of Synaptic Vesicles Relies on a Highly Conserved Protein MachineryThe Synapsins Are Important for Vesicle Restraint and MobilizationSNARE Proteins Catalyze Fusion of Vesicles with the Plasma MembraneCalcium Binding to Synaptotagmin Triggers Transmitter ReleaseThe Fusion Machinery Is Embedded in a Conserved Protein Scaffold at the Active ZoneModulation of Transmitter Release Underlies Synaptic PlasticityActivity-Dependent Changes in Intracellular Free Calcium Can Produce Long-Lasting Changes in ReleaseAxo-axonic Synapses on Presynaptic Terminals Regulate Transmitter ReleaseAn Overall View SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessbiomedicalscience.mhmedical.com/content.aspx?aid=1101678276 ER -