TY - CHAP M1 - Book, Section TI - Seizures and Epilepsy Y1 - 2014 N1 - T2 - Principles of Neural Science, Fifth Edition AB - Classification of Seizures and the Epilepsies Is Important for Pathogenesis and TreatmentSeizures Are Temporary Disruptions of Brain FunctionEpilepsy Is the Chronic Condition of Recurrent SeizuresThe Electroencephalogram Represents the Collective Behavior of Cortical NeuronsFocal Seizures Originate Within a Small Group of Neurons Known as a Seizure FocusNeurons in a Seizure Focus Have Characteristic ActivityThe Breakdown of Surround Inhibition Leads to SynchronizationThe Spread of Focal Seizures Involves Normal Cortical CircuitryPrimary Generalized Seizures Are Driven by Thalamocortical CircuitsLocating the Seizure Focus Is Critical to the Surgical Treatment of EpilepsyProlonged Seizures Can Cause Brain DamageRepeated Convulsive Seizures Are a Medical EmergencyExcitotoxicity Underlies Seizure-Related Brain DamageThe Factors Leading to Development of Epilepsy Are an Unfolding MysteryAmong the Genetic Causes of Epilepsy Are Ion Channel MutationsEpilepsies Involving Focal Seizures May Be a Maladaptive Response to InjuryAn Overall View SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessbiomedicalscience.mhmedical.com/content.aspx?aid=1101682822 ER -