TY - CHAP M1 - Book, Section TI - Marfan Syndrome A1 - Pyeritz, Reed E. A2 - Murray, Michael F. A2 - Babyatsky, Mark W. A2 - Giovanni, Monica A. A2 - Alkuraya, Fowzan S. A2 - Stewart, Douglas R. Y1 - 2014 N1 - T2 - Clinical Genomics: Practical Applications in Adult Patient Care AB - Disease summary:Marfan syndrome (MFS) is a relatively common heritable disorder of connective tissue that affects many tissues and organs, most prominently the ocular, cardiovascular, and musculoskeletal systems. The natural history predicts early demise, typically from aortic dissection. However, advances in medical and surgical management over the past three decades have extended life expectancy to near normal. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/09 UR - accessbiomedicalscience.mhmedical.com/content.aspx?aid=1102699651 ER -