TY - CHAP M1 - Book, Section TI - Genetic Toxicology A1 - Julian Preston, R. A1 - Hoffmann, George R. A2 - Klaassen, Curtis D. A2 - Watkins III, John B. Y1 - 2015 N1 - T2 - Casarett & Doull’s Essentials of Toxicology, 3e AB - Genetic toxicology assesses the effects of chemical and physical agents on the hereditary material (DNA) and on the genetic processes of living cells.Oncogenes are genes that stimulate the transformation of normal cells into cancer cells.Genetic toxicology assays serve to identify mutagens for purposes of hazard identification, and to characterize dose–response relationships and mutagenic mechanisms.A broad range of short-term assays for genetic toxicology serve to identify many mutagens and address the relationship between mutagens and cancer-causing agents. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accessbiomedicalscience.mhmedical.com/content.aspx?aid=1113949635 ER -