TY - CHAP M1 - Book, Section TI - Hematopoietic Agents: Growth Factors, Minerals, and Vitamins A1 - Hilal-Dandan, Randa A1 - Brunton, Laurence L. PY - 2016 T2 - Goodman and Gilman's Manual of Pharmacology and Therapeutics, 2e AB - The finite life span of most mature blood cells requires their continuous replacement, a process termed hematopoiesis. New cell production must respond to basal needs and states of increased demand. Red blood cell production can increase >20-fold in response to anemia or hypoxemia, white blood cell production increases dramatically in response to a systemic infection, and platelet production can increase 10- to 20-fold when platelet consumption results in thrombocytopenia. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/09 UR - accessbiomedicalscience.mhmedical.com/content.aspx?aid=1127551779 ER -