TY - CHAP M1 - Book, Section TI - OSTEOMYELITIS A1 - Zimmerli, Werner A2 - Kasper, Dennis L. A2 - Fauci, Anthony S. PY - 2017 T2 - Harrison's Infectious Diseases, 3e AB - Osteomyelitis, an infection of bone, can be caused by various microorganisms that arrive at bone through different routes. Spontaneous hematogenous osteomyelitis may occur in otherwise healthy individuals, whereas local microbial spread mainly affects either individuals who have underlying disease (e.g., vascular insufficiency) or patients who have compromised skin or other tissue barriers, with consequent exposure of bone. The latter situation typically follows surgery involving bone, such as sternotomy or orthopedic repair. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/09 UR - accessbiomedicalscience.mhmedical.com/content.aspx?aid=1141406248 ER -