TY  - CHAP
M1  - Book, Section
TI  - ZIKA VIRUS INFECTION AND ZIKA-ASSOCIATED CONGENITAL ABNORMALITIES
A1  - Morens, David M.
A1  - Fauci, Anthony S.
A2  - Kasper, Dennis L.
A2  - Fauci, Anthony S.
PY  - 2017
T2  - Harrison's Infectious Diseases, 3e
AB  - Zika  is  a  mosquito-borne  virus  that  is  closely  related  to  the  dengue  viruses  and  within  the  same  taxonomic  family  as  yellow  fever  virus.  Although  the  majority  of  human  Zika  virus  infections  are  asymptomatic  or  so  mild  that  they  may  go  unrecognized,  ~20%  of  infections  result  in  dengue-like  illnesses  with  fever,  myalgia,  and  rash.  Long  an  obscure  virus  of  little  human  consequence,  Zika  has  since  2013  spread  pandemically  and  directionally  around  the  globe  from  Southeast  Asia  to  the  South  Pacific  Islands;  in  2015–2016,  it  spread  to  South  and  Central  America  and  the  Caribbean  (Figure  108-1),  including  the  U.S.  Commonwealth  of  Puerto  Rico  and  the  Territory  of  the  U.S.  Virgin  Islands  (USVI).  From  these  epidemics,  travel-related  cases  and  exported  cases  were  observed  in  2016  in  all  50  U.S.  states  and  the  District  of  Columbia  as  well  as  in  many  other  nations.  Many  primary  care  and  other  providers  thus  face  diagnosing  Zika  cases  and  counseling  patients  about  both  actual  Zika  risks  and  unfounded  fears.  During  this  recent  pandemic  spread,  Zika  has  been  temporally  and  geographically  linked  in  some  countries  to  fetal  development  of  microcephaly  and  other  birth  defects.  In  adults,  Zika  infection  has  been  linked  to  Guillain-Barré  syndrome  and  possibly  to  apparently  rare  cases  of  acute  meningoencephalitis  and  myelitis.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/18
UR  - accessbiomedicalscience.mhmedical.com/content.aspx?aid=1141412427
ER  -