TY - CHAP M1 - Book, Section TI - Propagated Signaling: The Action Potential A1 - Kandel, Eric R. A1 - Koester, John D. A1 - Mack, Sarah H. A1 - Siegelbaum, Steven A. PY - 2021 T2 - Principles of Neural Science, 6e AB - NERVE CELLS ARE ABLE TO CARRY electrical signals over long distances because the long-distance signal, the action potential, is continually regenerated and thus does not attenuate as it moves down the axon. In Chapter 9, we saw how an action potential arises from sequential changes in the membrane’s permeability to Na+ and K+ ions and how the membrane’s passive properties influence the speed at which the action potential is conducted. In this chapter, we describe in detail the voltage-gated ion channels that are critical for generating and propagating action potentials and consider how these channels are responsible for important features of a neuron’s electrical excitability. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/03/28 UR - accessbiomedicalscience.mhmedical.com/content.aspx?aid=1180640398 ER -