TY - CHAP M1 - Book, Section TI - Tamoxifen Pharmacogenetics A1 - Zembutsu, Hitoshi A1 - Nakamura, Yusuke A2 - Murray, Michael F. A2 - Babyatsky, Mark W. A2 - Giovanni, Monica A. A2 - Alkuraya, Fowzan S. A2 - Stewart, Douglas R. PY - 2014 T2 - Clinical Genomics: Practical Applications in Adult Patient Care AB - Drug summary:Tamoxifen is widely used antiestrogen therapy for pre- and postmenopausal women with metastatic breast cancer, for prevention of recurrence as adjuvant therapy, and for women with a high risk of developing breast cancer as chemoprevention.Five years of adjuvant tamoxifen safely reduces 15-year risks of breast cancer recurrence.The most frequent adverse events by tamoxifen treatment is hot flash (>60%). SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/16 UR - accessbiomedicalscience.mhmedical.com/content.aspx?aid=1102698622 ER -