RT Book, Section
A1 Molinoff, Perry B.
A2 Brunton, Laurence L.
A2 Chabner, Bruce A.
A2 Knollmann, Björn C.
SR Print(0)
ID 1127865986
T1 Neurotransmission and the Central Nervous System
T2 Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 12e
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 9780071624428
LK accessbiomedicalscience.mhmedical.com/content.aspx?aid=1127865986
RD 2023/09/22
AB Drugs  that  act  in  the  central  nervous  system  (CNS)  are  invaluable  therapeutically.  They  can,  e.g.,  relieve  pain,  reduce  fever,  suppress  disordered  movements,  induce  sleep  or  arousal,  reduce  appetite,  and  allay  the  tendency  to  vomit.  Selectively  acting  drugs  can  be  used  to  treat  anxiety,  depression,  mania,  or  schizophrenia  and  do  so  without  altering  consciousness  (Chapters  15  and  16).  Socially  acceptable  stimulants  and  anti-anxiety  agents  contribute  to  emotional  stability,  relief  of  anxiety,  and  pleasure.  However,  the  excessive  use  of  such  drugs  can  affect  lives  adversely  when  uncontrolled,  self-administration  leads  to  physical  dependence  or  to  toxic  side  effects  (Chapter  24).  The  nonmedical  self-administration  of  CNS-active  drugs—  recreational  pharmacology—is  widespread.