RT Book, Section A1 McNamara, James O. A2 Brunton, Laurence L. A2 Chabner, Bruce A. A2 Knollmann, Björn C. SR Print(0) ID 1127866834 T1 Pharmacotherapy of the Epilepsies T2 Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 12e YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 9780071624428 LK accessbiomedicalscience.mhmedical.com/content.aspx?aid=1127866834 RD 2023/03/21 AB The epilepsies are common and frequently devastating disorders, affecting ~2.5 million people in the U.S. alone. More than 40 distinct forms of epilepsy have been identified. Epileptic seizures often cause transient impairment of consciousness, leaving the individual at risk of bodily harm and often interfering with education and employment. Therapy is symptomatic in that available drugs inhibit seizures, but neither effective prophylaxis nor cure is available. Compliance with medication is a major problem because of the need for long-term therapy together with unwanted effects of many drugs.