RT Book, Section
A1 Jameson, J. Larry
A1 Mandel, Susan J.
A1 Weetman, Anthony P.
A2 Jameson, J. Larry
SR Print(0)
ID 1141274506
T1 Disorders of the Thyroid Gland
T2 Harrison's Endocrinology, 4e
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9781259835728
LK accessbiomedicalscience.mhmedical.com/content.aspx?aid=1141274506
RD 2024/04/25
AB The  thyroid  gland  produces  two  related  hormones,  thyroxine  (T4)  and  triiodothyronine  (T3)  (Fig.  7-1).  Acting  through  thyroid  hormone  receptors  α  and  β,  these  hormones  play  a  critical  role  in  cell  differentiation  during  development  and  help  maintain  thermogenic  and  metabolic  homeostasis  in  the  adult.  Autoimmune  disorders  of  the  thyroid  gland  can  stimulate  overproduction  of  thyroid  hormones  (thyrotoxicosis)  or  cause  glandular  destruction  and  hormone  deficiency  (hypothyroidism).  In  addition,  benign  nodules  and  various  forms  of  thyroid  cancer  are  relatively  common  and  amenable  to  detection  by  physical  examination.