RT Book, Section
A1 Arlt, Wiebke
A2 Jameson, J. Larry
SR Print(0)
ID 1141274646
T1 Disorders of the Adrenal Cortex
T2 Harrison's Endocrinology, 4e
YR 2017
FD 2017
PB McGraw-Hill Education
PP New York, NY
SN 9781259835728
LK accessbiomedicalscience.mhmedical.com/content.aspx?aid=1141274646
RD 2024/04/20
AB The  adrenal  cortex  produces  three  classes  of  corticosteroid  hormones:  glucocorticoids  (e.g.,  cortisol),  mineralocorticoids  (e.g.,  aldosterone),  and  adrenal  androgen  precursors  (e.g.,  dehydroepiandrosterone  [DHEA])  (Fig.  8-1).  Glucocorticoids  and  mineralocorticoids  act  through  specific  nuclear  receptors,  regulating  aspects  of  the  physiologic  stress  response  as  well  as  blood  pressure  and  electrolyte  homeostasis.  Adrenal  androgen  precursors  are  converted  in  the  gonads  and  peripheral  target  cells  to  sex  steroids  that  act  via  nuclear  androgen  and  estrogen  receptors.